Startups in Denver and Boulder: Top 20 Funded Companies (2026)
Vantage Data Centers and Crusoe are fueling a massive funding year for startups in Denver and Boulder. See the full list of top companies here.
Published April 22, 2026 by Jacob Klionsky
- 01Hardware • Information Technology•Colorado$1.6BEquity
Leading global hyperscale data center provider Vantage Data Centers secured a $1.6B APAC platform investment led by GIC and ADIA; DigitalBridge and existing investors participated.
- 02Artificial Intelligence (AI) • Data and Analytics•Colorado$1.4BSeries E
AI-infrastructure provider Crusoe Energy Systems raised a $1.375 billion Series E co-led by Valor Equity Partners and Mubadala Capital, with dozens of institutional and strategic investors participating.
- 03Hardware • Information Technology•Colorado$500MPrivate Equity
Vero Networks, a fiber infrastructure and broadband provider, secured a $500 million non-control growth equity investment led by funds managed by Hamilton Lane, Braemont Capital and Delta-v Capital.
- 04Health Care • Information Technology•Colorado$300MSeries D
Value-based kidney care provider Strive Health raised a $300M Series D equity and $250M debt led by NEA and Hercules Capital; investors include CVS Health Ventures, CapitalG, Echo Health Ventures, Town Hall Ventures, Redpoint, and BlackRock affiliates.
- 05Hardware • Information Technology•Colorado$260.2MFunding Round
Wholesale colocation provider STACK Infrastructure secured a ¥39.7 billion ($247.7 million) green loan underwritten by Natixis CIB and Societe Generale to fund its 36 MW Tokyo data center campus.
- 06Energy • Manufacturing•Colorado$186MSeries B
Electra, a clean iron company, raised a $186M Series B led by Capricorn Investment Group and Temasek; Breakthrough Energy Ventures, Lowercarbon Capital, BHP Ventures, Builders Vision, and others also participated.
- 07Biotechnology • Health Care•Colorado$150MSeries D
AI-driven natural-products drug-discovery company Enveda raised a $150M Series D led by Premji Invest; Baillie Gifford, Kinnevik, Lingotto Investment Management and others participated.
- 08Energy • Manufacturing•Colorado$130MEquity
Utility-scale battery storage developer Peregrine Energy Solutions raised $130 million in new capital from the Ministry of Environment of South Korea, IMM Investment, Woori Private Equity Asset Management and AB CarVal.
- 09Biotechnology • Health Care•Colorado$100MSeries B
Ambrosia Biosciences, a small-molecule metabolic drug discovery company, raised $100 million in an oversubscribed Series B led by Blue Owl Healthcare Opportunities, Redmile and Deep Track Capital, with participation from BVF Partners, Boulder Ventures, Janus Henderson Investors, Samsara BioCapital and an undisclosed institutional investor.
- 10Biotechnology • Health Care•Colorado$55MSeries A
Think Bioscience, a synthetic-biology drug discovery startup, raised a $55 M Series A led by Regeneron Ventures, Innovation Endeavors, and Janus Henderson Investors with additional participation from T.A. Springer, CE-Ventures, MBX Capital, YK Bioventures, and returning backers AV8 Ventures, CU Innovations, and Buff Gold Ventures.
- 11Consumer Electronics • Consumer Goods•Colorado$50MEquity
Drone entertainment company Nova Sky Stories raised a $50M funding round with participation from WndrCo.
- 12Data and Analytics • Health Care•Colorado$43MEquity
VieCure, an AI oncology software startup, raised a $43 million funding round led by Mitch Rales and Northpond Ventures, with participation from Durable Capital Partners, Socium Ventures, and Sator Grove Holdings.
- 13Hardware•Colorado$40MSeries B
Maybell Quantum, a quantum infrastructure company, raised a $40M Series B led by Addition.
- 14Real Estate • Software•Colorado$35MEquity
FieldFlo, a project and safety management SaaS for specialty subcontractors, raised a $35 million growth equity round from Mainsail Partners.
- 15Information Technology • Privacy and Security•Colorado$31MSeries A
Cybersecurity-as-a-service startup RADICL Defense raised a $31 million Series A led by Paladin Capital Group, with participation from Access Venture Partners, Denver Ventures, and Cervin Ventures.
- 16Data and Analytics • Information Technology•Colorado$24MSeries A
Atolio, a private AI-powered enterprise search startup, raised $24M Series A led by Translink Capital; IBM Ventures, Bloomberg Beta, Acorn Pacific Ventures, and Parameter Ventures participated.
- 17Artificial Intelligence (AI) • Data and Analytics•Colorado$22MSeries A
Northslope, an applied-AI platform built for Palantir, secured a $22 M Series A co-led by Friends & Family Capital and Goldcrest Capital.
- 18Financial Services • Real Estate•Colorado$20MSeries B
Retirement solutions company for landlords Flock raised a $20M Series B led by Renegade Partners; a16z, Primary Venture, Susa, 1Sharpe and others participated.
- 19Blockchain and Cryptocurrency • Financial Services•Colorado$20MEquity
Two Prime, an institutional bitcoin yield manager, received a $20M equity investment led by MARA with participation from Susquehanna Crypto; MARA also expanded its allocation to 2,000 BTC.
- 20Biotechnology • Health Care•Colorado$17.3MSeries B
VitriVax, a thermostable vaccine platform startup, raised a $17.25 million Series B round led by Adjuvant Capital and RA Capital Management.
