Top Startups in Boston
Boston is surging with mega-rounds for firms like Commonwealth Fusion and Suno. Discover the top startups driving the city's hard-tech innovation boom.
- 01Energy • Science and Engineering•Massachusetts$863MSeries B
Commonwealth Fusion Systems, a fusion power startup building tokamaks, raised an $863M Series B2 from Nvidia, Google, Breakthrough Energy Ventures, Gates Frontier, and others.
- 02Government and Military • Manufacturing•Massachusetts$550MEquity
Vulcan Elements, a domestic rare earth magnet manufacturer, secured a $1.4 billion partnership financing package with the United States Government and ReElement Technologies.
- 03Biotechnology • Health Care•Massachusetts$305MSeries F
Parabilis Medicines, developer of Helicon peptide cancer therapeutics, raised a $305 million Series F round co-led by RA Capital Management, Fidelity Management & Research Company, and Janus Henderson Investors.
- 04Artificial Intelligence (AI) • Data and Analytics•Massachusetts$250MSeries C
AI music generator Suno raised a $250 million Series C round led by Menlo Ventures with participation from NVentures, Hallwood Media, Lightspeed, and Matrix.
- 05Artificial Intelligence (AI) • Data and Analytics•Massachusetts$250MSeries D
OpenEvidence, an AI medical search engine, raised a $250 million Series D led by Thrive Capital and DST Global.
- 06Consumer Electronics • Data and Analytics•Massachusetts$230MEquity
Neutral-atom quantum computing startup QuEra Computing raised over $230 million in a new financing round led by Google Quantum AI and SoftBank Vision Fund 2 with participation from NVentures (NVIDIA) and other global investors.
- 07Biotechnology • Health Care•Massachusetts$213MSeries D
Clinical-stage autoimmune therapeutics Odyssey Therapeutics raised a $213M Series D with participation from Affinity Asset Advisors, Dimension Capital, Jeito Capital, Lightspeed Ventures, TPG Life Sciences Innovations and others.
- 08Artificial Intelligence (AI) • Biotechnology•Massachusetts$200MSeed
Lila Sciences, an AI-driven scientific superintelligence and autonomous-lab startup, raised a $200 million seed round from Flagship Pioneering, General Catalyst, March Capital, ARK Venture Fund, Altitude Life Science Ventures, Blue Horizon Advisors, State of Michigan Retirement System, Modi Ventures and an ADIA subsidiary.
- 09Biotechnology • Health Care•Massachusetts$177MSeries A
Precision medicines biotech spin-out Antares raised a $177M Series A co-led by Omega Funds, Atlas Venture, Lightspeed Venture Partners, BVF Partners, and Cormorant Asset Management.
- 10Artificial Intelligence (AI) • Data and Analytics•Massachusetts$175MEquity
AI-native weather intelligence startup Tomorrow.io raised a $175M equity financing led by Stonecourt Capital and HarbourVest Partners to accelerate deployment of its DeepSky satellite constellation.
- 11Biotechnology • Health Care•Massachusetts$155MSeries B
AIRNA, an RNA editing therapeutics company, raised a $155M Series B led by Venrock Healthcare Capital Partners; co‑led by Forbion Growth, with participation from RTW, Nextech Invest, ARCH, ND Capital, and others
- 12Biotechnology • Health Care•Massachusetts$153MSeries B
Strand Therapeutics, a programmable mRNA therapeutics company, raised a $153M Series B led by Kinnevik; new investors Regeneron Ventures, ICONIQ, Amgen Ventures, Alderline Group, LG Technology Ventures and others participated.
- 13Hardware • Media and Entertainment•Massachusetts$150MSeries B
Teradar, a terahertz automotive sensor startup, raised a $150 million Series B equity round from Capricorn Investment Group, Lockheed Martin Ventures, IBEX Investors and VXI Capital.
- 14Artificial Intelligence (AI) • Data and Analytics•Massachusetts$140MSeries G
Aura, an AI-powered online safety company, raised a $140 million Series G round of equity and debt led by Ten Eleven Ventures and Madrone Capital with participation from AT&T Ventures, Accel, Warburg Pincus and General Catalyst.
- 15Biotechnology • Health Care•Massachusetts$132MSeries B
Clinical-stage radiopharmaceutical company ARTBIO raised a $132M Series B co-led by Sofinnova Investments and B Capital; F-Prime, Omega Funds, Third Rock Ventures and others participated.
- 16Artificial Intelligence (AI) • Consumer Electronics•Massachusetts$130MSeries A
Autonomous cybersecurity startup Seven AI raised a $130 million Series A led by Index Ventures with participation from Blackstone Innovations Investments, Greylock, CRV and Spark.
- 17Biotechnology • Health Care•Massachusetts$121MSeries A
Precision immunology biotech Merida Biosciences raised $121M Series A co-led by Bain Capital Life Sciences, BVF Partners and Third Rock Ventures, with participation from GV and Perceptive Xontogeny Venture Funds.
- 18Biotechnology • Health Care•Massachusetts$120MSeries B
Atavistik Bio, a precision allosteric therapeutics developer, raised a $120 M Series B led by Nextech Invest and The Column Group with participation from Lux Capital and Regeneron Ventures.
- 19Artificial Intelligence (AI) • Biotechnology•Massachusetts$110MSeries E
AI-driven drug discovery company Insilico Medicine raised a $110M Series E led by Value Partners Group, with participation from industry- and technology-focused new investors and existing global backers.
- 20Health Care•Massachusetts$103MSeries B
Kinaset Therapeutics, developer of an inhaled pan-JAK therapy for severe asthma, raised a $103 million Series B round co-led by RA Capital Management and Forge Life Science Partners.
